廣東省高等學(xué)?！扒О偈こ獭钡谒呐囵B(yǎng)對(duì)象
[學(xué)位/學(xué)歷]
博士（香港大學(xué)）
[學(xué)術(shù)簡歷]
1988-1993?? ?中山醫(yī)科大學(xué)口腔醫(yī)學(xué)系?學(xué)士
1993-1998?? ?中山醫(yī)科大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院?住院醫(yī)師、主治醫(yī)師,、助教
1998-2002?? ?香港大學(xué)牙醫(yī)學(xué)院?博士
2002-2004?? ?中山大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院?講師
2004-2009?? ?中山大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院??副主任醫(yī)師
2006至今?? ?中山大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院?口腔種植學(xué)?碩士研究生導(dǎo)師
2009至今????中山大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院?主任醫(yī)師
2012至今?? ?中山大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院?口腔種植學(xué)?博士研究生導(dǎo)師
2014至今?? ?中山大學(xué)光華口腔醫(yī)學(xué)院·附屬口腔醫(yī)院?教授
2017至今?? ?廣東省口腔醫(yī)學(xué)會(huì)口腔種植專委會(huì)?主任委員
2018至今?? ??中華口腔醫(yī)學(xué)會(huì)口腔種植專業(yè)委員會(huì)?? ? ?副主任委員
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[研究方向]
口腔種植治療中植骨材料的基礎(chǔ)與臨床研究
種植體周圍炎的機(jī)制與治療
數(shù)字化口腔種植治療的臨床應(yīng)用
[主持課題]
2004?? ?廣東省自然科學(xué)基金(04300294)：納米磷灰石晶體在仿生溶液鈦金屬表面生長的研究
2004?? ??廣東省醫(yī)學(xué)科研基金(B2004059)：鈦基納米磷灰石在仿生溶液中生長的研究
2005?? ??國家自然科學(xué)基金(30500570)：羥基磷灰石在模擬體液的溶解平衡研究
2006?? ??廣東省科技攻關(guān)項(xiàng)目(31003004)：羥基磷灰石溶解度體外測(cè)試系統(tǒng)的建立
2007?? ??中山大學(xué)橫向合作課題(7101001)：不同類型羥基磷灰石溶解度及其影響因素研究
2009?? ??國家自然科學(xué)基金(30973355)：離子植入影響生物骨陶瓷材料降解性能的實(shí)驗(yàn)研究
2010?? ??中山大學(xué)青年教師基金(10ykpy16)：氟離子摻雜生物磷灰石的體內(nèi)外實(shí)驗(yàn)研究
2011 ? ??廣東省自然科學(xué)基金(S2011010004978)：氟離子改性生物磷灰石體外降解及生物學(xué)性能實(shí)驗(yàn)研究
2014 ??國家自然科學(xué)基金(81470783)：氟化生物源性羥基磷灰石溶解平衡與促進(jìn)成骨的機(jī)制研究
2015 ? ??廣東省自然科學(xué)基金?-?重點(diǎn)（2015A03031105）：豬骨羥基磷灰石氟離子摻雜后溶解平衡與成骨性能的研究
2019 ? ?國家自然科學(xué)基金(81970975)：Zn-nHA/PLGA/FBHA復(fù)合材料通過調(diào)控?Th17/Treg細(xì)胞平衡影響種植體周圍炎骨微環(huán)境促進(jìn)骨缺損修復(fù)的研究
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[發(fā)表論文]
1.?? ? ? ? ?Liu GQ#, Guo YL#, Zhang LJ#, Wang XS, Liu RH, Huang PN, XiaoY,?Chen Z*, Chen ZT*. Astandardized rat burr hole defect model to study maxillofacial boneregeneration, Acta Biomaterialia, 2019, 86, 450-464.
2.?? ? ? ? ?Wu SY#, Xia BB#, Mai S#, Feng ZC, Wang XS, Liu YD, Liu RH, LiZP, Xiao Y*,?Chen Z*, ChenZT*. Sodium fluoride under dose range of 2.424 μM, a promisingosteoimmunomodulatory agent for vascularized bone formation, ACS BiomaterialsScience and Engineering, 2019, 5(2), 817-830.
3.?? ? ? ? ??QiaoW#, Liu RH#, LiZP, Luo X, Huang BX, Liu Q, Chen ZT, Tsoi J, Su YX, Cheung K, Matinlinna JP*,Yeung Kelvin*,Chen Z*. In situ release of endogenouscations from xenograft bone driven by fluoride incorporation contributes toenhanced bone regeneration, Biomaterials Science, 2018, 6, 2951-2964.
4.?? ? ? ? ?Chen ZT, Chen LL, Liu RH, Lin YX, Chen SC, Lu S, Lin ZM,?ChenZ, Chengtie Wu, Yin Xiao. The osteoimmunomodulatory property of barriercollagen membrane and its manipulation via coating nanometer-sized bioactiveglass to improve guided bone regeneration, Biomaterials Science, 2018, 1;6(5): 1007-1019.
5.?? ? ? ? ?Liu RH, Qiao W, Huang BX, Chen ZT, Fang JH, Li ZP,?Chen Z.Fluorination enhances osteogenic capacity of porcine hydroxyapatite, TissueEngineering Part A, 2018,?24(15-16): 1207-1217.
6.?? ? ? ? ?Liu RH#, Lin YX#, Lin JY#,Zhang LJ, Mao XL, Huang BX, Xiao Y,ChenZ*, Chen ZT*. BloodPrefabrication Subcutaneous Small Animal Model for the Evaluation of BoneSubstitute Materials,?ACS Biomaterials Science andEngineering, 2018, 4, 7, 2516-2527.
7.?? ? ? ? ?Chen SC, Guo YL, Liu RH, Wu SY, Fang JH, Huang BX, Li ZP,?ChenZ, Chen ZT. Tuning surface properties of bone biomaterials to manipulateosteoblastic cell adhesion and the downstream signaling pathways for theenhancement of early osseointegration, Colloids and Surfaces B: Biointerfaces,2018, 164, 58-69.
8.?? ? ? ? ?Wu S,，Wu X，Shrestha R,，Lin J,，F(xiàn)eng Z，Liu Y,，Shi Y,，Huang B，Li Z,，Liu Q,，Zhang X, Hu M,?Chen Z.Clinical and Radiologic Outcomes of Submerged and Nonsubmerged Bone-LevelImplants with Internal Hexagonal Connections in Immediate Implantation: A5-Year Retrospective Study. Journal of Prosthodontics, 2018, 27, 2, 101-107.
9.?? ? ? ? ?Han A, Tsoi J, Matinlinna JP, Zhang Y,?Chen Z. Effectsof different sterilization methods on surface characteristics and biofilmformation on zirconia in vitro[J]. Dental Materials, 2018, 34, 2, 272-281.
10.?? ? ??Han A, Tsoi J, Matinlinna JP,?Chen Z. Influence ofGrit-Blasting and Hydrofluoric Acid Etching Treatment on SurfaceCharacteristics and Biofilm Formation on Zirconia[J]. Coatings, 2017, 7(8):130.
11.?? ? ??Qiao W, Liu Q, Li ZP, Zhang HQ,?Chen Z. Changes inphysicochemical and biological properties of porcine bone derivedhydroxyapatite induced by the incorporation of fluoride.[J]. Sci Technol AdvMater, 2017, 18(1):110-121.
12.?? ? ??Liu Q,?Chen Z, Pan HB, Darvell BW, Matinlinna JP.Effect of Magnesium on the Solubility of Hydroxyapatite[J]. European Journal ofInorganic Chemistry, 2016, 2016(36).
13.?? ? ??Han AF, Li XL, Huang BX, Tsoi J, Matinlinna JP,?Chen Z,Deng DM. The effect of titanium implant surface modification on the dynamicprocess of initial microbial adhesion and biofilm formation[J]. InternationalJournal of Adhesion & Adhesives, 2016, 69:125-132.
14.?? ? ??Li ZP, Huang BX, Mai S, Wu XY, Zhang HQ, Qiao W, Luo X,?ChenZ. Effects of fluoridation of porcine hydroxyapatite on osteoblasticactivity of human MG63 cells. Sci Technol Advan Mater, 2015, 16(3):1099-1020.
15.?? ? ??Yin L, Yu Z,?Chen Z, Huang B, Zhang K, Zhou A, et al.Analysis of Bone Height Changes after Maxillary Sinus Augmentation withSimultaneous and Delayed Placement of Dental Implants: A Clinical andRadiographic Study. J Prosthodont. 2015 Jul 27. (IF 1.071)
16.?? ? ??Li Z, Yi J, Huang B, Wu X, Qiao W, Luo X,?Chen Z.Ultraviolet irradiation enhanced bioactivity and biological response ofmesenchymal stem cells on micro-arc oxidized titanium surfaces. Dent Mater J.2015;34(2):135–47.?（IF 0.968）
17.?? ? ??Liu Q, Pan H,?Chen Z, Matinlinna JP. Insight intobone-derived biological apatite: ultrastructure and effect of thermaltreatment. Biomed Res Int. 2015; 2015:601025.(IF 1.579)
18.?? ? ??Chen Z, Feng S, Pow EHN, Lam OLT, Mai S, Wang H. Organic anioncomposition of human whole saliva as determined by ion chromatography. ClinChim Acta. 2014 Aug 30;438C:231–5.(IF 2.764)
19.?? ? ??Liu Q,?Chen Z, Pan HB, Darvell, BW. The effect ofexcess phosphate on the solubility of hydroxyapatite. Ceram Int. 2014; 40:2751-61. (IF 2.086)
20.?? ? ??Liu Q, Huang SS, Matinlinna JP,?Chen Z, Pan HB.Insight into Biological Apatite: Physiochemical Properties and PreparationApproaches. Biomed Research International. 2013: 13. (IF 2.706)
21.?? ? ??Wang DY, Kunzel A, Golubovic V., Mihatovic I., John G.,?ChenZ, Becker J., Schwarz F. More about accuracy of peri-implant bone thicknessand validity of assessing bone augmentation material using cone beam computedtomography. Clin Oral Invest. 2013; 17: 1787-88. (IF 2.285)
22.?? ? ??Wang D, Künzel A, Golubovic V, Mihatovic I, John G,?Chen Z,Becker J, Schwarz F*. Accuracy of peri-implant bone thickness and validity ofassessing bone augmentation material using cone beam computed tomography. ClinOral Investig. 2013 Jul;17(6):1601-1609.?(IF 2.285)
23.?? ? ??Liu Q, Chen Z, Gu H,?Chen Z.?Preparation and characterization of fluorinated porcine hydroxyapatite.?Dent Mater J.2012;31(5):742-50. (IF=0.943)
24.?? ? ??Liu JY, Pow EHN,?Chen Z,?Zheng J, Zhang XC, Chen J. Themandarin Chinese shortened version of oral health impact profile for partiallyedentate patients with implant-supported prostheses. J Oral Rehabil. 2012?Aug;39(8):591-9.(IF 1.934)
25.?? ? ??Zheng GS, Su YX, Liao GQ,?Chen Z, Wang L, Jiao PF, LiuHC, Zhong YQ, Zhang TH, Liang YJ. Mandible reconstruction assisted bypreoperative virtual surgical simulation.?Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2012May;113(5):604-11.?(IF 1.417)
27.?? ? ??Pan HB,?Chen ZF, Darvell BW. Solubility ofsparingly-soluble electrolytes–a new approach. Anal Methods,2010, 2(7):?973-975?? ?(IF1.938)
28.?? ? ??Chen ZF*,?Huang BX,?Pan HB,?Darvell BW. Solubility of bovine-derivedhydroxyapatite by solid titration, pH3.5-5.?Crystal Growth & Design, 2009, 9(6):2816-2820?? ? (IF 4.215)
29.?? ? ??Chen ZF, Pow EH. A technique for the fabrication of an immediateimplant-supported provisional restoration using a fractured natural tooth.??J Prosthet Dent, 2008, 100(2): 157-158?? ?(IF 1.009)
30.?? ? ??Chen ZF*, Pow HN, Wang Y, Luo ZB.Clinical evaluation of ceramic implant abutments in anterior restorations.Annals of the Royal Australasian College of Dental Surgeons, 2008,19:67-70?? ?(NA)
31.?? ? ??Chen ZF, Darvell BW, Leung VWH. Validation of ion chromatography forhuman salivary anionic analysis.??ArchOral Biol, 2004, 49(11): 855-862?? (IF1.554)
32.?? ? ??Chen ZF, Darvell BW, Leung VWH. Human salivary anionic analysisusing ion chromatography.??Arch OralBiol, 2004, 49(11): 863-869?? (IF 1.554)
33.?? ? ??Chen ZF, Darvell BW, Leung VWH. Hydroxyapatite solubility in simpleinorganic solutions.??Arch Oral Biol, 2004,49(5): 359-367?? (IF 1.554)
[參編教材與論著]
1.???《口腔種植治療的基礎(chǔ)研究與臨床應(yīng)用》
（陳卓凡?主編. 2010年4月第1版.?北京:人民軍醫(yī)出版社，ISBN: 978-7-5091-3639-3.）
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2.??《口腔種植學(xué)》
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（林野?主編.?陳卓凡?參編. 2014年7月第一版.?北京：北京大學(xué)醫(yī)學(xué)出版社,，ISBN：9787565907586.）
3.???《頜骨腫瘤診斷與治療》
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（陶謙?主編.?陳卓凡?參編.??2008年1月第一版.?上海：上?？茖W(xué)技術(shù)出版社，ISBN：9787532394265.）
[獲獎(jiǎng)及學(xué)術(shù)榮譽(yù)]
2008年（首屆） “中華口腔醫(yī)學(xué)會(huì)－登士柏口腔醫(yī)學(xué)青年人才獎(jiǎng)”
[社會(huì)兼職]
1.?中華口腔醫(yī)學(xué)會(huì)口腔種植專業(yè)委員會(huì)?? ? ?副主任委員
2. 廣東省口腔醫(yī)學(xué)會(huì)口腔種植學(xué)專業(yè)委員會(huì) ?主任委員
3.香港大學(xué)牙醫(yī)學(xué)院??榮譽(yù)教授（Honorary Professor）
4. 香港口腔種植學(xué)會(huì) ?副會(huì)長
5. Implant Dentistry ?Editor (Council/Section)
6. 中華口腔醫(yī)學(xué)研究雜志（電子版） 編委
[聯(lián)系方式]
地 址：廣州市陵園西路56號(hào)中山大學(xué)光華口腔醫(yī)學(xué)院?附屬口腔醫(yī)院（510055）
電 話：020-83862537
傳 真：020-83822807
E-mail：[email protected]
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